UCSF Update on Heart Failure Therapies – 2025

Description

Hearts in Sonoma: UCSF Update on Heart Failure Therapies – 2025

Videos+PDFs

Overview

Heart failure affects approximately seven million Americans and is the most common diagnosis for acute hospitalization in patients over sixty-five years of age, with numbers increasing dramatically over the coming decades. UCSF Update on Heart Failure Therapies will feature up-to-date presentations on the evaluation and treatment of heart failure from initial diagnosis to advanced therapies. This conference will cover the success of guideline directed care, remote monitoring in the treatment and management of chronic heart failure, new approaches and innovations in the areas of cardiogenic shock, acute and long term mechanical circulatory support devices, heart transplantation, novel valvular heart disease therapeutics, genetic cardiomyopathies, cardiac amyloidosis and management of right heart failure and pulmonary hypertension. A comprehensive, advanced heart failure program can integrate treatment advances into a comprehensive patient-centered heart failure management program.

Target Audience
This course is designed for practicing internists, cardiologists, family practitioners, advanced practice providers, nurses, pharmacists, and all other healthcare professionals taking care of heart failure patients.

Objectives

Describe the latest guideline updates in the treatment and management of heart failure (HF), including optimization of drug therapy, remote monitoring, and novel clinical interventions and clinical trials;
Describe current approaches for the management of cardiogenic shock and the use of acute mechanical circulatory support devices in these patients. Highlight the importance of partnership with a quaternary care center cardiogenic shock team to facilitate rapid transfer of the patient in refractory cardiogenic shock.
Describe the use of long-term durable LVADs in patients with advanced heart failure, our minimally invasive surgical implant techniques, and the UCSF shared care programs with community cardiologists and co-management of patients;
Describe the latest innovations in heart transplant care, including novel approaches for organ acquisition, preservation, and procurement, dual organ transplantation, and expanded donor criteria leading to increased donor pool and decreased waiting times;
Review management of pulmonary hypertension in advanced heart failure: challenges and successes;
Discuss therapies and review new era drugs and strategies for the management of cardiac amyloidosis;
Discuss the comprehensive multidisciplinary care and services available to manage complex cardiac patients through the evolution of their disease pre- and post advanced cardiac intervention, and UCSF’s commitment to linking with community physicians.

Course Outline

Friday, September 12, 2025
Time	Title	Speaker(s)
7:00 – 8:00am	Registration/Continental Breakfast Kenwood Foyer/Sonoma Valley Room Product Theater (Kenwood Room-Full Breakfast) – Kiniksa Pharmaceuticals Arcalyst: EVIDENCE-BASED TREATMENT OF RECURRENT PERICARDITIS	John Ryan, MD
8:05 – 8:30	New Pillars of HFpEF Management	Pooja Prasad, MD
8:35 – 9:00	Improving Heart Failure Care by Treating its Comorbidities	Shweta Motiwala, MD
9:05 – 9:30	New Heart Failure Devices	Liviu Klein, MD
9:35 – 10:15	Heart Failure Clinic: the Cornerstone of Patient Care	Shweta Motiwala, MD Brandon Martinez, PharmD Robin Fischer, DNP Jamie Lee, RN Yuri Nam, NP
10:15 – 10:30	Break
10:35 – 11:00	Multimodal Imaging in Cardiomyopathies	Michael Salerno, MD
11:05 – 11:30	Amyloid Cardiomyopathy: a Cinderella no More!	Mandar Aras, MD, PhD
11:35 – 12:00	What’s New in Pulmonary Hypertension?	Marc Simon, MD
12:00 – 12:45	Hosted Lunch
12:50 – 1:30	Risk-Based Prevention of Heart Failure: A New Paradigm	Donald M. Lloyd-Jones, MD, ScM
1:40 – 2:05	Early Recognition of Advanced Heart Failure	Leila Beach, MD
2:10 – 2:35	The Rise of the Machines: LVADs for Long-Term Heart Failure Therapy	Mandar Aras, MD
2:35 – 2:50	Break
2:50 – 3:15	Heart Transplantation in 2025: Back to the Future	Amy Fiedler, MD
3:15 – 3:50	Multidisciplinary Care: the Key to the Success of Transplant and LVAD Care	Jose Lazo, PharmD Julia Galeota, MSW Marvin Mailom, RN Simran Grewal, NP Ashley Jannesen, NP
4:00 – 4:30	GUARDIAN Angel: Organ Transport Updates	Amy Fiedler, MD Liviu Klein, MD
5:30 – 7:30 pm	Garden Reception
Saturday, September 13, 2025
Time	Title	Speaker(s)
7:00 – 8:05 am	Continental Breakfast Sonoma Valley Room Product Theater (Kenwood Room-Full Breakfast) – Alnylam Pharmaceuticals Introduction to AMVUTTRA (Vutrisiran) for the treatment of ATTR-CM and hATTR-PN in Adults	Mandar Aras, MD, PhD
8:05 – 8:25	A Primer for Non-Transplant Providers in Caring for Heart Transplant Patients	Jaqueline DesJardin, MD
8:30 – 8:55	Cardiogenic Shock after DanGer	Connor O’Brien, MD
9:00 – 10:00	What if a Heart Transplant or LVAD Patient Show up in my ER (case studies)	Connor O’Brien, MD Jaqueline DesJardin, MD Faculty Panel
10:00 – 10:15	Break
10:15 – 11:55	Collaboration for Complex Cases: Bring your Challenging cases to Discuss	Amy Fiedler, MD Connor O’Brien Liviu Klein, MD Community cardiologists Faculty Panel