USCAP Tutorial in Pathology of the GI Tract, Pancreas and Liver 2026

Course Overview

Pathologists working with gastrointestinal (GI) specimens play a crucial and expanding role in modern disease management. With increasing use of endoscopy and advanced tissue acquisition methods, the volume and complexity of GI samples have grown significantly.

This course focuses on:

• Accurate diagnosis using limited biopsy material
• Use of immunohistochemistry & molecular analysis
• Identification of druggable targets & genetic conditions
• Pattern recognition in liver and GI diseases
• Clinical decision support for complex GI cases

👉 Designed to provide practical, concise, and real-world diagnostic guidance.

📌 Includes digital slides (WSI) for each case — can be viewed as unknowns or alongside lectures.

🎯 Target Audience

• Pathologists
• Gastrointestinal pathology specialists
• Medical professionals involved in GI diagnostics

🧠 Key Learning Areas / Modules

🧬 Liver & Biliary Pathology

• Liver Anatomy and Histology
• Metabolic Diseases of the Liver
• Medication-Related Injury & Infections
• Hepatitic & Biliary Injury Patterns
• Vascular & Unusual Liver Injury Patterns
• Solid Tumors of Liver & Bile Ducts
• Cystic & Vascular Liver Tumors

🍽️ GI Tract Pathology

• Esophagitis Patterns
• Gastritides (Common & Uncommon)
• Chronic Colitis (2026 Approach)
• Enteropathies (Emerging & Common)
• Appendicitis & Appendiceal Neoplasia

🔬 Oncology & Tumors

• Early Esophageal & Gastric Neoplasia
• GI Tumor Reporting
• Immunohistochemical Biomarkers
• Metastatic Carcinoma of Unknown Primary
• GIST and Mimics
• Mesenchymal Tumors (Rare Types)

🧪 Pancreas & Gallbladder

• Pancreatic Tumors (Neuroendocrine & Others)
• Pancreatic Duct Neoplasms
• Gallbladder & Ampulla Tumors

🧩 Special Topics

• GI Polyposis Syndromes
• GI Manifestations of Systemic Diseases
• Expert Case Discussions

Liver Anatomy and Histology – John Hart, MD
Section: 1 Presentation, 1 Document

Metabolic Diseases of the Liver – Sanjay Kakar, MD
Section: 1 Presentation, 1 Document

Medication Related Injury and Infections in the Liver – John Hart, MD
Section: 1 Presentation, 3 Documents

Hepatitic and Biliary Patterns of Liver Injury: The Art and Science of Pattern Recognition – Sanjay Kakar, MD
Section: 1 Presentation, 3 Documents

Neoplastic and Non-Neoplastic Anal Pathology – Elizabeth A. Montgomery, MD
Section: 1 Presentation, 2 Documents

Approach to Early Esophageal and Gastric Neoplasia – Elizabeth A. Montgomery, MD
Section: 1 Presentation, 1 Document

Interpretation of Immunohistochemical Biomarkers in Gastrointestinal Cancers – Rondell P. Graham, MBBS
Section: 1 Presentation, 1 Document

Solid Tumors of the Liver and Bile Ducts – Rondell P. Graham, MBBS
Section: 1 Presentation, 2 Documents

Beyond Typical Hepatitic and Biliary Diseases: Vascular and Other Unusual Patterns of Liver Injury – Sanjay Kakar, MD
Section: 1 Presentation, 3 Documents

Patterns of Esophagitis and Their Meaning – Rhonda K. Yantiss, MD
Section: 1 Presentation, 2 Documents

Metastatic Carcinoma of Unknown Primary: The Role of Immunohistochemistry (Stay in Control!) – Jason L. Hornick, MD, PhD
Section: 1 Presentation, 1 Document

Reporting Endoscopic Samples of GI Tumors – Rhonda K. Yantiss, MD
Section: 1 Presentation, 1 Document

Common and Uncommon Gastritides – Elizabeth A. Montgomery, MD
Section: 1 Presentation, 2 Documents

Appendicitis and Appendiceal Neoplasia – Rhonda K. Yantiss, MD
Section: 1 Presentation, 2 Documents

When to Suggest the Possibility of GI Polyposis Syndrome in Routine Surgical Pathology Sign-Out – John Hart, MD
Section: 1 Presentation, 2 Documents

Breakfast with the Expert, John Hart, MD Shares His All-Time Favorite Cases – John Hart, MD
Section: 1 Presentation, 1 Document

GIST and Mimics: The Good, the Bad, and the Ugly – Jason L. Hornick, MD, PhD
Section: 1 Presentation, 2 Documents

Approach to Chronic Colitis in 2026 – Nicole C. Panarelli, MD
Section: 1 Presentation, 2 Documents

Cystic and Vascular Tumors of the Liver – Rondell P. Graham, MBBS
Section: 1 Presentation, 2 Documents

Even Less Common Mesenchymal Tumors in the GI Tract – Jason L. Hornick, MD, PhD
Section: 1 Presentation, 2 Documents

Biopsy Diagnosis of Common and Emerging Enteropathies – Nicole C. Panarelli, MD
Section: 1 Presentation, 1 Document

Tumors of the Gallbladder and Ampulla – Olca Basturk, MD
Section: 1 Presentation, 1 Document

Neuroendocrine and Other Solid Cellular Tumors of the Pancreas in Biopsy and Resection Specimens – Olca Basturk, MD
Section: 1 Presentation, 2 Documents

Gastrointestinal Manifestations of Systemic Diseases in Immunocompetent and Immunocompromised Patients – Nicole C. Panarelli, MD
Section: 1 Presentation, 2 Documents

Neoplasms of the Pancreatic Ducts: Frozen Sections, Small Biopsies, and Challenging Resection Specimens – Olca Basturk, MD
Section: 1 Presentation, 2 Documents